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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX1
All Species:
15.15
Human Site:
S458
Identified Species:
30.3
UniProt:
Q9NRD9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD9
NP_787954.1
1551
177235
S458
Q
D
I
N
P
A
L
S
R
S
N
D
T
V
L
Chimpanzee
Pan troglodytes
XP_001163196
1551
177072
S458
Q
D
I
N
P
A
L
S
R
S
N
D
T
V
L
Rhesus Macaque
Macaca mulatta
XP_001111340
1551
176921
F458
Q
D
I
N
P
V
L
F
R
S
N
D
T
V
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001092767
1551
177113
S458
Q
D
I
N
P
A
L
S
R
S
N
G
T
V
L
Rat
Rattus norvegicus
Q8CIY2
1551
177179
S458
Q
D
I
N
P
A
L
S
R
S
N
G
T
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
S461
T
S
W
K
D
F
N
S
S
V
D
P
E
V
L
Chicken
Gallus gallus
XP_425053
1523
173782
T436
L
E
P
L
Q
D
W
T
N
L
A
P
H
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
S291
F
L
G
T
H
V
T
S
Y
P
G
Y
Q
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
H419
E
S
Y
G
L
K
R
H
K
T
W
T
D
I
N
Honey Bee
Apis mellifera
XP_624355
1492
172466
N440
K
K
T
W
N
E
I
N
P
E
L
F
N
K
N
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
N431
D
N
G
V
P
P
Y
N
E
L
R
R
T
F
G
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
F570
H
A
D
G
V
E
T
F
I
D
S
E
V
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.7
N.A.
N.A.
91
90.1
N.A.
73.9
65.1
N.A.
47.1
N.A.
39.9
40.3
34.3
41.6
Protein Similarity:
100
99.4
97.8
N.A.
N.A.
95
94.4
N.A.
84.4
78.4
N.A.
61.7
N.A.
58
60.2
55.9
59.3
P-Site Identity:
100
100
86.6
N.A.
N.A.
93.3
93.3
N.A.
20
0
N.A.
6.6
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
86.6
N.A.
N.A.
93.3
93.3
N.A.
26.6
13.3
N.A.
6.6
N.A.
26.6
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
34
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
42
9
0
9
9
0
0
0
9
9
25
9
0
9
% D
% Glu:
9
9
0
0
0
17
0
0
9
9
0
9
9
0
0
% E
% Phe:
9
0
0
0
0
9
0
17
0
0
0
9
0
9
0
% F
% Gly:
0
0
17
17
0
0
0
0
0
0
9
17
0
0
9
% G
% His:
9
0
0
0
9
0
0
9
0
0
0
0
9
0
0
% H
% Ile:
0
0
42
0
0
0
9
0
9
0
0
0
0
9
0
% I
% Lys:
9
9
0
9
0
9
0
0
9
0
0
0
0
17
0
% K
% Leu:
9
9
0
9
9
0
42
0
0
17
9
0
0
9
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
42
9
0
9
17
9
0
42
0
9
0
17
% N
% Pro:
0
0
9
0
50
9
0
0
9
9
0
17
0
0
0
% P
% Gln:
42
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
0
0
9
0
42
0
9
9
0
0
0
% R
% Ser:
0
17
0
0
0
0
0
50
9
42
9
0
0
9
0
% S
% Thr:
9
0
9
9
0
0
17
9
0
9
0
9
50
0
0
% T
% Val:
0
0
0
9
9
17
0
0
0
9
0
0
9
50
0
% V
% Trp:
0
0
9
9
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
0
9
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _